The Monastery of San Jerónimo de Yuste is located in the province of Cáceres, in the autonomous community of Extremadura, Spain.

It was founded by the Hieronymite Order in 1402. In 1556, Charles V, the Holy Roman Emperor settled here after his abdication and remained until his death two years later. A palace was built for him and his court, which is now integral part of the site, along with surrounding gardens. 

The activity of the Yuste Foundation, which has its headquarters at the site, is aimed at promoting European integration and values such as democracy or respect for human rights. Its work includes debating on the current and future challenges of the European Union and its relationship with Ibero-America. Its flagship project is the Carlos V European Award given to prominent European leaders and politician.